Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3

Ubiquitin signalling is a fundamental eukaryotic regulatory system, controlling diverse cellular functions. A cascade of E1, E2, and E3 enzymes is required for assembly of distinct signals, whereas an array of deubiquitinases and ubiquitin-binding modules edit, remove, and translate the signals. In...

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Detalles Bibliográficos
Autores principales: Alpi, Arno F., Chaugule, Viduth, Walden, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095918/
https://www.ncbi.nlm.nih.gov/pubmed/27729585
http://dx.doi.org/10.1042/BCJ20160028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095918/
https://www.ncbi.nlm.nih.gov/pubmed/27729585
http://dx.doi.org/10.1042/BCJ20160028

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