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The differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferation

BACKGROUND: High-risk human papillomaviruses (HPVs) are strongly associated with the development of some malignancies. The E6 and E7 viral oncoproteins are the primary proteins responsible for cell homeostasis alteration and immortalization. Furthermore, the E6 protein from high-risk HPVs can intera...

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Detalles Bibliográficos
Autores principales: Stuqui, Bruna, Conceição, André Luis Giacometti, Termini, Lara, Sichero, Laura, Villa, Luisa Lina, Rahal, Paula, Calmon, Marília de Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095955/
https://www.ncbi.nlm.nih.gov/pubmed/27809811
http://dx.doi.org/10.1186/s12885-016-2873-1