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Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model
BACKGROUND: Mutations of Crb1 gene cause irreversible and incurable visual impairment in humans. This study aims to use an LCA8-like mouse model to identify host-mediated responses that might interfere with survival, retinal integration and differentiation of grafted cells during neonatal cell thera...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095973/ https://www.ncbi.nlm.nih.gov/pubmed/27809828 http://dx.doi.org/10.1186/s12886-016-0368-0 |