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How to talk about protein‐level false discovery rates in shotgun proteomics

A frequently sought output from a shotgun proteomics experiment is a list of proteins that we believe to have been present in the analyzed sample before proteolytic digestion. The standard technique to control for errors in such lists is to enforce a preset threshold for the false discovery rate (FD...

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Detalles Bibliográficos
Autores principales: The, Matthew, Tasnim, Ayesha, Käll, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096025/
https://www.ncbi.nlm.nih.gov/pubmed/27503675
http://dx.doi.org/10.1002/pmic.201500431