Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

BACKGROUND: Abnormalities in ureteric bud (UB) branching morphogenesis lead to congenital anomalies of the kidney and reduced nephron numbers associated with chronic kidney disease (CKD) and hypertension. Previous studies showed that the epithelial fibroblast growth factor receptor 2 (Fgfr2) IIIb sp...

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Detalles Bibliográficos
Autores principales: Bebee, Thomas W., Sims‐Lucas, Sunder, Park, Juw Won, Bushnell, Daniel, Cieply, Benjamin, Xing, Yi, Bates, Carlton M., Carstens, Russ P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096029/
https://www.ncbi.nlm.nih.gov/pubmed/27404344
http://dx.doi.org/10.1002/dvdy.24431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096029/
https://www.ncbi.nlm.nih.gov/pubmed/27404344
http://dx.doi.org/10.1002/dvdy.24431

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