Cargando…

Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

BACKGROUND: Abnormalities in ureteric bud (UB) branching morphogenesis lead to congenital anomalies of the kidney and reduced nephron numbers associated with chronic kidney disease (CKD) and hypertension. Previous studies showed that the epithelial fibroblast growth factor receptor 2 (Fgfr2) IIIb sp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bebee, Thomas W., Sims‐Lucas, Sunder, Park, Juw Won, Bushnell, Daniel, Cieply, Benjamin, Xing, Yi, Bates, Carlton M., Carstens, Russ P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096029/ https://www.ncbi.nlm.nih.gov/pubmed/27404344 http://dx.doi.org/10.1002/dvdy.24431

Ejemplares similares

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
por: Bebee, Thomas W, et al.
Publicado: (2015)

Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
por: Lee, SungKyoung, et al.
Publicado: (2018)

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation
por: Bhate, Amruta, et al.
Publicado: (2015)

Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms
por: Yang, Yueqin, et al.
Publicado: (2017)

Ablation of the Renal Stroma Defines Its Critical Role in Nephron Progenitor and Vasculature Patterning
por: Hum, Stephanie, et al.
Publicado: (2014)

Functional roles of alternative splicing factors in human disease
por: Cieply, Benjamin, et al.
Publicado: (2015)

The global Protein-RNA interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
por: Peart, Natoya J., et al.
Publicado: (2022)

The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina
por: Murphy, Daniel, et al.
Publicado: (2016)

Altered Ureteric Branching Morphogenesis and Nephron Endowment in Offspring of Diabetic and Insulin-Treated Pregnancy
por: Hokke, Stacey N., et al.
Publicado: (2013)

Abstract 94: Esrp1 Loss Disrupts MicroRNAs Which Target Wnt Signaling Required For Palatogenesis
por: Wilson, Nathan, et al.
Publicado: (2020)

Abstract 91: High-Resolution Gene Expression Analysis of RNA Splicing Regulators Esrp1 and Esrp2 In Palate Development
por: Carroll, Shannon H., et al.
Publicado: (2019)

Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer
por: Freytag, Morton, et al.
Publicado: (2020)

Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT
por: Harvey, Samuel E., et al.
Publicado: (2018)

An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates
por: Carroll, Shannon H., et al.
Publicado: (2020)

Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes
por: Burguera, Demian, et al.
Publicado: (2017)

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer
por: Munkley, Jennifer, et al.
Publicado: (2019)

GLI3 Repressor Controls Nephron Number via Regulation of Wnt11 and Ret in Ureteric Tip Cells
por: Cain, Jason E., et al.
Publicado: (2009)

Clinicopathological assessment of the nephron number
por: Tsuboi, Nobuo, et al.
Publicado: (2014)

Betaglycan Is Required for the Establishment of Nephron Endowment in the Mouse
por: Walker, Kenneth A., et al.
Publicado: (2011)

The number of nephrons in different glomerular diseases
por: Viggiano, Davide, et al.
Publicado: (2019)

MITF – A controls branching morphogenesis and nephron endowment
por: Phelep, Aurélie, et al.
Publicado: (2017)

Endothelial Progenitors Exist within the Kidney and Lung Mesenchyme
por: Sims-Lucas, Sunder, et al.
Publicado: (2013)

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data
por: Shen, Shihao, et al.
Publicado: (2012)

The RNA Binding Protein RBM38 (RNPC1) Regulates Splicing during Late Erythroid Differentiation
por: Heinicke, Laurie A., et al.
Publicado: (2013)

European synchrotron radiation facility: report of the ESRP
por: Tazzari, Sergio, et al.
Publicado: (1984)

Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA
por: Wang, Wenjun, et al.
Publicado: (2023)

Loss of peri-Wolffian duct stromal Frs2α expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux
por: Narla, Deepti, et al.
Publicado: (2017)

Low Nephron Number and Its Clinical Consequences
por: Luyckx, Valerie A., et al.
Publicado: (2011)

Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration
por: Short, Kieran M, et al.
Publicado: (2018)

The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
por: Legge, Danny, et al.
Publicado: (2021)

Integrated Analysis of Structural Variation and RNA Expression of FGFR2 and Its Splicing Modulator ESRP1 Highlight the ESRP1(amp)-FGFR2(norm)-FGFR2-IIIc(high) Axis in Diffuse Gastric Cancer
por: Teles, Sara Pinto, et al.
Publicado: (2019)

Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral Reflux
por: Walker, Kenneth A., et al.
Publicado: (2013)

Correction: Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral Reflux
por: Walker, Kenneth A., et al.
Publicado: (2016)

Downregulated ESRP1/2 promotes lung metastasis of bladder carcinoma through altering FGFR2 splicing and macrophage polarization
por: Zhao, Yuyang, et al.
Publicado: (2023)

Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma
por: Anslow, Melissa J., et al.
Publicado: (2020)

The ESRP1-GPR137 axis contributes to intestinal pathogenesis
por: Mager, Lukas Franz, et al.
Publicado: (2017)

The Regulation of Apoptosis in Kidney Development: Implications for Nephron Number and Pattern?
por: Ho, Jacqueline
Publicado: (2014)

Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury
por: Narla, Sridhar Tatarao, et al.
Publicado: (2022)

ISG15 induces ESRP1 to inhibit lung adenocarcinoma progression
por: Qu, Tongyuan, et al.
Publicado: (2020)

Hypoxia-induced TGF-β–RBFOX2–ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer
por: Ahuja, Neha, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8gh9ksqt0fq6t0jddbmfqe7if8