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Chaperonin–Dendrimer Conjugates for siRNA Delivery

The group II chaperonin thermosome (THS) is a hollow protein nanoparticle that can encapsulate macromolecular guests. Two large pores grant access to the interior of the protein cage. Poly(amidoamine) (PAMAM) is conjugated into THS to act as an anchor for small interfering RNA (siRNA), allowing to l...

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Detalles Bibliográficos
Autores principales: Nussbaumer, Martin G., Duskey, Jason T., Rother, Martin, Renggli, Kasper, Chami, Mohamed, Bruns, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096033/
https://www.ncbi.nlm.nih.gov/pubmed/27840795
http://dx.doi.org/10.1002/advs.201600046