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Chaperonin–Dendrimer Conjugates for siRNA Delivery
The group II chaperonin thermosome (THS) is a hollow protein nanoparticle that can encapsulate macromolecular guests. Two large pores grant access to the interior of the protein cage. Poly(amidoamine) (PAMAM) is conjugated into THS to act as an anchor for small interfering RNA (siRNA), allowing to l...
Autores principales: | Nussbaumer, Martin G., Duskey, Jason T., Rother, Martin, Renggli, Kasper, Chami, Mohamed, Bruns, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096033/ https://www.ncbi.nlm.nih.gov/pubmed/27840795 http://dx.doi.org/10.1002/advs.201600046 |
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