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Kinetics of the Interactions between Copper and Amyloid‐β with FAD Mutations and Phosphorylation at the N terminus

Mutations and post‐translational modifications of amyloid‐β (Aβ) peptide in its N terminus have been shown to increase fibril formation, yet the molecular mechanism is not clear. Here we investigated the kinetics of the interactions of copper with two Aβ peptides containing Familial Alzheimer's...

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Detalles Bibliográficos
Autores principales: Girvan, Paul, Miyake, Toru, Teng, Xiangyu, Branch, Thomas, Ying, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096041/
https://www.ncbi.nlm.nih.gov/pubmed/27356100
http://dx.doi.org/10.1002/cbic.201600255