A Short Synthesis of Aphanamol I in Both Racemic and Enantiopure Forms

A short synthesis of the biologically active sesquiterpene natural product (+)‐aphanamol I in both racemic and enantiopure forms is reported. Key steps include: a catalytic enantioselective conjugate addition, an oxidative radical cyclization, and a ring‐expanding Claisen rearrangement.

Detalles Bibliográficos
Autores principales: Ferrara, Steven J., Burton, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096262/
https://www.ncbi.nlm.nih.gov/pubmed/27389970
http://dx.doi.org/10.1002/chem.201602669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096262/
https://www.ncbi.nlm.nih.gov/pubmed/27389970
http://dx.doi.org/10.1002/chem.201602669

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