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Integrin Alpha 9 Blockade Suppresses Lymphatic Valve Formation and Promotes Transplant Survival

PURPOSE: The lymphatic pathway mediates transplant rejection. We recently reported that lymphatic vessels develop luminal valves in the cornea during lymphangiogenesis, and these valves express integrin alpha 9 (Itga-9) and play a critical role in directing lymph flow. In this study, we used an allo...

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Detalles Bibliográficos
Autores principales: Kang, Gyeong Jin, Truong, Tan, Huang, Eric, Su, Valerie, Ge, Shaokui, Chen, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096415/
https://www.ncbi.nlm.nih.gov/pubmed/27806381
http://dx.doi.org/10.1167/iovs.16-20130