A Novel Null Mutation in P450 Aromatase Gene (CYP19A1) Associated with Development of Hypoplastic Ovaries in Humans

OBJECTIVE: The CYP19A1 gene product aromatase is responsible for estrogen synthesis and androgen/estrogen equilibrium in many tissues, particularly in the placenta and gonads. Aromatase deficiency can cause various clinical phenotypes resulting from excessive androgen accumulation and insufficient e...

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Detalles Bibliográficos
Autores principales: Akçurin, Sema, Türkkahraman, Doğa, Kim, Woo-Young, Durmaz, Erdem, Shin, Jae-Gook, Lee, Su-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096477/
https://www.ncbi.nlm.nih.gov/pubmed/27086564
http://dx.doi.org/10.4274/jcrpe.2761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096477/
https://www.ncbi.nlm.nih.gov/pubmed/27086564
http://dx.doi.org/10.4274/jcrpe.2761

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