Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo

Prions are a group of proteins that can adopt a spectrum of metastable conformations in vivo. These alternative states change protein function and are self-replicating and transmissible, creating protein-based elements of inheritance and infectivity. Prion conformational flexibility is encoded in th...

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Detalles Bibliográficos
Autores principales: Langlois, Christine R., Pei, Fen, Sindi, Suzanne S., Serio, Tricia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096688/
https://www.ncbi.nlm.nih.gov/pubmed/27814358
http://dx.doi.org/10.1371/journal.pgen.1006417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096688/
https://www.ncbi.nlm.nih.gov/pubmed/27814358
http://dx.doi.org/10.1371/journal.pgen.1006417

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