Synthesis, anti-inflammatory, analgesic, COX1/2-inhibitory activity, and molecular docking studies of hybrid pyrazole analogues

This article reports on the design, synthesis, and pharmacological activity of a new series of hybrid pyrazole analogues: 5a–5u. Among the series 5a–5u, the compounds 5u and 5s exhibited potent anti-inflammatory activity of 80.63% and 78.09% and inhibition of 80.87% and 76.56% compared with the stan...

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Detalles Bibliográficos
Autores principales: Alam, Md Jahangir, Alam, Ozair, Khan, Suroor Ahmad, Naim, Mohd Javed, Islamuddin, Mohammad, Deora, Girdhar Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096746/
https://www.ncbi.nlm.nih.gov/pubmed/27826185
http://dx.doi.org/10.2147/DDDT.S118297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096746/
https://www.ncbi.nlm.nih.gov/pubmed/27826185
http://dx.doi.org/10.2147/DDDT.S118297

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