Cargando…

Mast cell desensitization inhibits calcium flux and aberrantly remodels actin

Rush desensitization (DS) is a widely used and effective clinical strategy for the rapid inhibition of IgE-mediated anaphylactic responses. However, the cellular targets and underlying mechanisms behind this process remain unclear. Recent studies have implicated mast cells (MCs) as the primary targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ang, W.X. Gladys, Church, Alison M., Kulis, Mike, Choi, Hae Woong, Burks, A. Wesley, Abraham, Soman N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096925/
https://www.ncbi.nlm.nih.gov/pubmed/27669462
http://dx.doi.org/10.1172/JCI87492