Cargando…
Mast cell desensitization inhibits calcium flux and aberrantly remodels actin
Rush desensitization (DS) is a widely used and effective clinical strategy for the rapid inhibition of IgE-mediated anaphylactic responses. However, the cellular targets and underlying mechanisms behind this process remain unclear. Recent studies have implicated mast cells (MCs) as the primary targe...
Autores principales: | Ang, W.X. Gladys, Church, Alison M., Kulis, Mike, Choi, Hae Woong, Burks, A. Wesley, Abraham, Soman N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096925/ https://www.ncbi.nlm.nih.gov/pubmed/27669462 http://dx.doi.org/10.1172/JCI87492 |
Ejemplares similares
-
Mast Cell Desensitization in Allergen Immunotherapy
por: López-Sanz, Celia, et al.
Publicado: (2022) -
Mechanisms of Drug Desensitization: Not Only Mast Cells
por: Vultaggio, Alessandra, et al.
Publicado: (2020) -
Nasal Immunization With Small Molecule Mast Cell Activators Enhance Immunity to Co-Administered Subunit Immunogens
por: Johnson-Weaver, Brandi T., et al.
Publicado: (2021) -
Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury
por: Karhausen, Jörn, et al.
Publicado: (2020) -
Desensitization induces hyporesponsiveness and cell-surface phenotype changes on mouse mast cells
por: Giavina-Bianchi, Pedro, et al.
Publicado: (2014)