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mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors

Mammalian target of rapamycin complex 1 (mTORC1) has an essential role in dendritic mRNA translation and participates in mechanisms underlying alcohol-drinking and reconsolidation of alcohol-related memories. Here, we report that excessive alcohol consumption increases the translation of downstream...

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Detalles Bibliográficos
Autores principales: Liu, F, Laguesse, S, Legastelois, R, Morisot, N, Ben Hamida, S, Ron, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097030/
https://www.ncbi.nlm.nih.gov/pubmed/26952865
http://dx.doi.org/10.1038/mp.2016.12