Human corneal cell culture models for drug toxicity studies

In vivo toxicity and absorption studies of topical ocular drugs are problematic, because these studies involve invasive tissue sampling and toxic effects in animal models. Therefore, different human corneal models ranging from simple monolayer cultures to three-dimensional models have been developed...

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Detalles Bibliográficos
Autores principales: Rönkkö, Seppo, Vellonen, Kati-Sisko, Järvinen, Kristiina, Toropainen, Elisa, Urtti, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097077/
https://www.ncbi.nlm.nih.gov/pubmed/27613190
http://dx.doi.org/10.1007/s13346-016-0330-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097077/
https://www.ncbi.nlm.nih.gov/pubmed/27613190
http://dx.doi.org/10.1007/s13346-016-0330-y

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