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Human corneal cell culture models for drug toxicity studies
In vivo toxicity and absorption studies of topical ocular drugs are problematic, because these studies involve invasive tissue sampling and toxic effects in animal models. Therefore, different human corneal models ranging from simple monolayer cultures to three-dimensional models have been developed...
Autores principales: | Rönkkö, Seppo, Vellonen, Kati-Sisko, Järvinen, Kristiina, Toropainen, Elisa, Urtti, Arto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097077/ https://www.ncbi.nlm.nih.gov/pubmed/27613190 http://dx.doi.org/10.1007/s13346-016-0330-y |
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