Cytosolic Ku70 regulates Bax-mediated cell death

The first known function of Ku70 is as a DNA repair factor in the nucleus. Using neuronal neuroblastoma cells as a model, we have established that cytosolic Ku70 binds to the pro-apoptotic protein Bax in the cytosol and blocks Bax’s cell death activity. Ku70-Bax binding is regulated by Ku70 acetylat...

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Detalles Bibliográficos
Autores principales: Hada, Manila, Subramanian, Chitra, Andrews, Phillip C., Kwok, Roland P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097087/
https://www.ncbi.nlm.nih.gov/pubmed/27488115
http://dx.doi.org/10.1007/s13277-016-5202-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097087/
https://www.ncbi.nlm.nih.gov/pubmed/27488115
http://dx.doi.org/10.1007/s13277-016-5202-z

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