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Unexpected frequency of genomic alterations in histologically normal colonic tissue from colon cancer patients

As shown by genomic studies, colorectal cancer (CRC) is a highly heterogeneous disease, where copy number alterations (CNAs) may greatly vary among different patients. To explore whether CNAs may be present also in histologically normal tissues from patients affected by CRC, we performed CGH + SNP M...

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Detalles Bibliográficos
Autores principales: Conconi, Donatella, Redaelli, Serena, Bovo, Giorgio, Leone, Biagio Eugenio, Filippi, Emanuela, Ambrosiani, Luciana, Cerrito, Maria Grazia, Grassilli, Emanuela, Giovannoni, Roberto, Dalprà, Leda, Lavitrano, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097093/
https://www.ncbi.nlm.nih.gov/pubmed/27481518
http://dx.doi.org/10.1007/s13277-016-5181-0