IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells

Internal ribosome entry site (IRES)-mediated translation is a specialized mode of protein synthesis which malignant cells depend on to survive adverse microenvironmental conditions. Our lab recently reported the identification of a group of compounds which selectively interfere with IRES-mediated tr...

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Detalles Bibliográficos
Autores principales: Vaklavas, Christos, Grizzle, William E., Choi, Hyoungsoo, Meng, Zheng, Zinn, Kurt R., Shrestha, Kedar, Blume, Scott W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097113/
https://www.ncbi.nlm.nih.gov/pubmed/27460074
http://dx.doi.org/10.1007/s13277-016-5161-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097113/
https://www.ncbi.nlm.nih.gov/pubmed/27460074
http://dx.doi.org/10.1007/s13277-016-5161-4

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