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IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells
Internal ribosome entry site (IRES)-mediated translation is a specialized mode of protein synthesis which malignant cells depend on to survive adverse microenvironmental conditions. Our lab recently reported the identification of a group of compounds which selectively interfere with IRES-mediated tr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097113/ https://www.ncbi.nlm.nih.gov/pubmed/27460074 http://dx.doi.org/10.1007/s13277-016-5161-4 |