Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

Sensing bacterial products in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1 inflammasomes, and the production of the pro-inflammatory cytokines interleukin (IL)-18 and IL-1β. In addition, mouse caspase-11 (represented in humans by its orthologs, caspase-4...

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Detalles Bibliográficos
Autores principales: Thurston, Teresa L. M., Matthews, Sophie A., Jennings, Elliott, Alix, Eric, Shao, Feng, Shenoy, Avinash R., Birrell, Mark A., Holden, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097160/
https://www.ncbi.nlm.nih.gov/pubmed/27808091
http://dx.doi.org/10.1038/ncomms13292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097160/
https://www.ncbi.nlm.nih.gov/pubmed/27808091
http://dx.doi.org/10.1038/ncomms13292

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