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Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
Sensing bacterial products in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1 inflammasomes, and the production of the pro-inflammatory cytokines interleukin (IL)-18 and IL-1β. In addition, mouse caspase-11 (represented in humans by its orthologs, caspase-4...
Autores principales: | Thurston, Teresa L. M., Matthews, Sophie A., Jennings, Elliott, Alix, Eric, Shao, Feng, Shenoy, Avinash R., Birrell, Mark A., Holden, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097160/ https://www.ncbi.nlm.nih.gov/pubmed/27808091 http://dx.doi.org/10.1038/ncomms13292 |
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