Cargando…

Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling

Long non-coding RNAs (lncRNAs) are known players in the regulatory circuitry of the self-renewal in human embryonic stem cells (hESCs). However, most hESC-specific lncRNAs remain uncharacterized. Here we demonstrate that growth-arrest-specific transcript 5 (GAS5), a known tumour suppressor and growt...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Chen, Zhang, Yan, Wang, Qiaoling, Xu, Zhenyu, Jiang, Junfeng, Gao, Yuping, Gao, Minzhi, Kang, Jiuhong, Wu, Minjuan, Xiong, Jun, Ji, Kaihong, Yuan, Wen, Wang, Yue, Liu, Houqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097163/
https://www.ncbi.nlm.nih.gov/pubmed/27811843
http://dx.doi.org/10.1038/ncomms13287