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Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling

Long non-coding RNAs (lncRNAs) are known players in the regulatory circuitry of the self-renewal in human embryonic stem cells (hESCs). However, most hESC-specific lncRNAs remain uncharacterized. Here we demonstrate that growth-arrest-specific transcript 5 (GAS5), a known tumour suppressor and growt...

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Detalles Bibliográficos
Autores principales:	Xu, Chen, Zhang, Yan, Wang, Qiaoling, Xu, Zhenyu, Jiang, Junfeng, Gao, Yuping, Gao, Minzhi, Kang, Jiuhong, Wu, Minjuan, Xiong, Jun, Ji, Kaihong, Yuan, Wen, Wang, Yue, Liu, Houqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097163/ https://www.ncbi.nlm.nih.gov/pubmed/27811843 http://dx.doi.org/10.1038/ncomms13287

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