The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase

Biofilms play a major role in Staphylococcus aureus pathogenicity but respond poorly to antibiotics. Here, we show that the antifungal caspofungin improves the activity of fluoroquinolones (moxifloxacin, delafloxacin) against S. aureus biofilms grown in vitro (96-well plates or catheters) and in viv...

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Detalles Bibliográficos
Autores principales: Siala, Wafi, Kucharíková, Soňa, Braem, Annabel, Vleugels, Jef, Tulkens, Paul M, Mingeot-Leclercq, Marie-Paule, Van Dijck, Patrick, Van Bambeke, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097165/
https://www.ncbi.nlm.nih.gov/pubmed/27808087
http://dx.doi.org/10.1038/ncomms13286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097165/
https://www.ncbi.nlm.nih.gov/pubmed/27808087
http://dx.doi.org/10.1038/ncomms13286

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