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Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA
Translesion polymerase eta (polη) was characterized for its ability to replicate ultraviolet-induced DNA lesions that stall replicative polymerases, a process promoted by Rad18-dependent PCNA mono-ubiquitination. Recent findings have shown that polη also acts at intrinsically difficult to replicate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097173/ https://www.ncbi.nlm.nih.gov/pubmed/27811911 http://dx.doi.org/10.1038/ncomms13326 |