Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA

Translesion polymerase eta (polη) was characterized for its ability to replicate ultraviolet-induced DNA lesions that stall replicative polymerases, a process promoted by Rad18-dependent PCNA mono-ubiquitination. Recent findings have shown that polη also acts at intrinsically difficult to replicate...

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Detalles Bibliográficos
Autores principales: Despras, Emmanuelle, Sittewelle, Méghane, Pouvelle, Caroline, Delrieu, Noémie, Cordonnier, Agnès M, Kannouche, Patricia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097173/
https://www.ncbi.nlm.nih.gov/pubmed/27811911
http://dx.doi.org/10.1038/ncomms13326

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