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Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma
BACKGROUND: To evaluate the inhibitory effects of aflibercept on the growth and subretinal invasion of retinoblastoma. METHODS: Xenotransplantation and orthotopic mouse models were created by injecting Y-79 cells subcutaneously and intravitreally, respectively. After induction of retinoblastoma, ani...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097437/ https://www.ncbi.nlm.nih.gov/pubmed/27814771 http://dx.doi.org/10.1186/s13046-016-0451-7 |