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Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma

BACKGROUND: To evaluate the inhibitory effects of aflibercept on the growth and subretinal invasion of retinoblastoma. METHODS: Xenotransplantation and orthotopic mouse models were created by injecting Y-79 cells subcutaneously and intravitreally, respectively. After induction of retinoblastoma, ani...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Yoon, Choi, Jeong A, Koh, Jae-Young, Yoon, Young Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097437/ https://www.ncbi.nlm.nih.gov/pubmed/27814771 http://dx.doi.org/10.1186/s13046-016-0451-7

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