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Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

BACKGROUND: Complex diseases are characterized by multiple subtle perturbations to biological processes. New omics platforms can detect these perturbations, but translating the diverse molecular and statistical information into testable mechanistic hypotheses is challenging. Therefore, we set out to...

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Detalles Bibliográficos
Autores principales: Shu, Le, Zhao, Yuqi, Kurt, Zeyneb, Byars, Sean Geoffrey, Tukiainen, Taru, Kettunen, Johannes, Orozco, Luz D., Pellegrini, Matteo, Lusis, Aldons J., Ripatti, Samuli, Zhang, Bin, Inouye, Michael, Mäkinen, Ville-Petteri, Yang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097440/
https://www.ncbi.nlm.nih.gov/pubmed/27814671
http://dx.doi.org/10.1186/s12864-016-3198-9