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Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

We previously reported that polyploid giant cancer cells (PGCGs) induced by CoCl(2) could form through endoreduplication or cell fusion. A single PGCC formed tumors in immunodeficient mice. PGCCs are also the key contributors to the cellular atypia and associate with the malignant grade of tumors. P...

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Detalles Bibliográficos
Autores principales: Zhang, Shiwu, Zhang, Dan, Yang, Zhengduo, Zhang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097820/
https://www.ncbi.nlm.nih.gov/pubmed/27843459
http://dx.doi.org/10.1155/2016/4810734