A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System

Pain and stress are protective mechanisms essential in avoiding harmful or threatening stimuli and ensuring survival. Despite these beneficial roles, chronic exposure to either pain or stress can lead to maladaptive hormonal and neuronal modulations that can result in chronic pain and a wide spectru...

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Detalles Bibliográficos
Autores principales: Massaly, Nicolas, Morón, Jose A., Al-Hasani, Ream
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097922/
https://www.ncbi.nlm.nih.gov/pubmed/27872581
http://dx.doi.org/10.3389/fnins.2016.00480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097922/
https://www.ncbi.nlm.nih.gov/pubmed/27872581
http://dx.doi.org/10.3389/fnins.2016.00480

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