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4-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in rats

To examine the effects of 4-methylthio-3-butenyl isothiocyanate on esophageal carcinogenesis, male 6-week-old F344 rats were subcutaneously injected with 0.5 mg/kg body weight N-nitrosomethylbenzylamine three times per week for 5 weeks and fed a diet supplemented with 80 ppm 4-methylthio-3-butenyl i...

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Detalles Bibliográficos
Autores principales: Suzuki, Isamu, Cho, Young-Man, Hirata, Tadashi, Toyoda, Takeshi, Akagi, Jun-ichi, Nakamura, Yasushi, Park, Eun Young, Sasaki, Azusa, Nakamura, Takako, Okamoto, Shigehisa, Shirota, Koji, Suetome, Noboru, Nishikawa, Akiyoshi, Ogawa, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097966/
https://www.ncbi.nlm.nih.gov/pubmed/27821908
http://dx.doi.org/10.1293/tox.2016-0037