Celecoxib alleviates oxaliplatin-induced hyperalgesia through inhibition of spinal ERK1/2 signaling

Numerous pieces of evidence have revealed that oxaliplatin (OXA) evokes mechanical and cold hypersensitivity. However, the mechanism underlying these bothersome side effects needs to be further investigated. It is well known that cyclooxygenase-2 (COX-2) and extracellular signal-regulated kinases (E...

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Detalles Bibliográficos
Autores principales: Chen, Hongping, Wang, Qinghua, Shi, Danni, Yao, Dongbo, Zhang, Lei, Xiong, Junping, Xu, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097968/
https://www.ncbi.nlm.nih.gov/pubmed/27821910
http://dx.doi.org/10.1293/tox.2016-0032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097968/
https://www.ncbi.nlm.nih.gov/pubmed/27821910
http://dx.doi.org/10.1293/tox.2016-0032

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