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Acute alloxan toxicity causes granulomatous tubulointerstitial nephritis with severe mineralization
Alloxan had been recognized as having a direct nephrotoxic effect different from its diabetogenic action. We encountered previously unreported granulomatous tubulointerstitial nephritis with severe luminal and interstitial mineralization in one diabetic rat after one week of alloxan administration....
Autores principales: | Zhang, Lianshan, Terayama, Yui, Nishimoto, Taiki, Kodama, Yasushi, Ozaki, Kiyokazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097969/ https://www.ncbi.nlm.nih.gov/pubmed/27821911 http://dx.doi.org/10.1293/tox.2016-0017 |
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