mTOR Overactivation in Mesenchymal cells Aggravates CCl(4)− Induced liver Fibrosis

Hepatic stellate cells are of mesenchymal cell type located in the space of Disse. Upon liver injury, HSCs transactivate into myofibroblasts with increase in expression of fibrillar collagen, especially collagen I and III, leading to liver fibrosis. Previous studies have shown mTOR signaling is acti...

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Detalles Bibliográficos
Autores principales: Shan, Lanlan, Ding, Yan, Fu, You, Zhou, Ling, Dong, Xiaoying, Chen, Shunzhi, Wu, Hongyuan, Nai, Wenqing, Zheng, Hang, Xu, Wanfu, Bai, Xiaochun, Jia, Chunhong, Dai, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098141/
https://www.ncbi.nlm.nih.gov/pubmed/27819329
http://dx.doi.org/10.1038/srep36037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098141/
https://www.ncbi.nlm.nih.gov/pubmed/27819329
http://dx.doi.org/10.1038/srep36037

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