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HepaCAM associates with connexin 43 and enhances its localization in cellular junctions

HepaCAM (GlialCAM) is frequently deleted in carcinomas, and reintroduction of hepaCAM into transformed cell lines reduces cellular growth and induces senescence. Mutations in HEPACAM give rise to the neurodegenerative disease megalencephalic leukoencephalopathy with subcortical cysts (MLC) since mut...

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Detalles Bibliográficos
Autores principales: Wu, Meihui, Moh, Mei Chung, Schwarz, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098153/
https://www.ncbi.nlm.nih.gov/pubmed/27819278
http://dx.doi.org/10.1038/srep36218