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ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons

LIM-homeodomain (HD) transcription factors form a multimeric complex and assign neuronal subtype identities, as demonstrated by the hexameric ISL1-LHX3 complex which gives rise to somatic motor (SM) neurons. However, the roles of combinatorial LIM code in motor neuron diversification and their subse...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Tai, Kim, Namhee, Kim, Hwan-Ki, Lee, Hojae, Gruner, Hannah N., Gergics, Peter, Park, Chungoo, Mastick, Grant S., Park, Hae-Chul, Song, Mi-Ryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098159/
https://www.ncbi.nlm.nih.gov/pubmed/27819291
http://dx.doi.org/10.1038/srep36491