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Hyperglycaemia-induced reciprocal changes in miR-30c and PAI-1 expression in platelets

Type 2 diabetic mellitus (DM2) is associated with accelerated thrombotic complications and is characterized by high levels of plasminogen activator inhibitor-1 (PAI-1). Recent studies show that human platelets have high levels of miR-30c and synthesize considerable active PAI-1. The underlying mecha...

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Detalles Bibliográficos
Autores principales: Luo, Mao, Li, Rong, Ren, Meiping, Chen, Ni, Deng, Xin, Tan, Xiaoyong, Li, Yongjie, Zeng, Min, Yang, Yan, Wan, Qin, Wu, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098184/
https://www.ncbi.nlm.nih.gov/pubmed/27819307
http://dx.doi.org/10.1038/srep36687