An active IGF-1R-AKT signaling imparts functional heterogeneity in ovarian CSC population

Deregulated IGF-1R-AKT signaling influences multiple nodes of cancer cell physiology and assists in migration, metastasis and acquirement of radio/chemoresistance. Enrichment of cancer stem cells (CSC) positively correlates with radio/chemoresistance development in various malignancies. It is unclea...

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Detalles Bibliográficos
Autores principales: Singh, Ram K., Dhadve, Ajit, Sakpal, Asmita, De, Abhijit, Ray, Pritha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098199/
https://www.ncbi.nlm.nih.gov/pubmed/27819360
http://dx.doi.org/10.1038/srep36612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098199/
https://www.ncbi.nlm.nih.gov/pubmed/27819360
http://dx.doi.org/10.1038/srep36612

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