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A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients

Cellular locomotion is a central hallmark of eukaryotic life. It is governed by cell-extrinsic molecular factors, which can either emerge in the soluble phase or as immobilized, often adhesive ligands. To encode for direction, every cue must be present as a spatial or temporal gradient. Here, we dev...

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Detalles Bibliográficos
Autores principales: Schwarz, Jan, Bierbaum, Veronika, Merrin, Jack, Frank, Tino, Hauschild, Robert, Bollenbach, Tobias, Tay, Savaş, Sixt, Michael, Mehling, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098208/
https://www.ncbi.nlm.nih.gov/pubmed/27819270
http://dx.doi.org/10.1038/srep36440