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Structure and Function of FS50, a salivary protein from the flea Xenopsylla cheopis that blocks the sodium channel Na(V)1.5

Naturally occurring toxins have been invaluable tools for the study of structural and functional relationships of voltage-gated sodium channels (VGSC). Few studies have been made of potential channel-modulating substances from blood-feeding arthropods. He we describe the characterization FS50, a sal...

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Detalles Bibliográficos
Autores principales: Xu, Xueqing, Zhang, Bei, Yang, Shilong, An, Su, Ribeiro, José M. C., Andersen, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098211/
https://www.ncbi.nlm.nih.gov/pubmed/27819327
http://dx.doi.org/10.1038/srep36574