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Structure and Function of FS50, a salivary protein from the flea Xenopsylla cheopis that blocks the sodium channel Na(V)1.5
Naturally occurring toxins have been invaluable tools for the study of structural and functional relationships of voltage-gated sodium channels (VGSC). Few studies have been made of potential channel-modulating substances from blood-feeding arthropods. He we describe the characterization FS50, a sal...
Autores principales: | Xu, Xueqing, Zhang, Bei, Yang, Shilong, An, Su, Ribeiro, José M. C., Andersen, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098211/ https://www.ncbi.nlm.nih.gov/pubmed/27819327 http://dx.doi.org/10.1038/srep36574 |
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