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Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R

CD200R is an inhibitory receptor expressed on myeloid cells and some lymphoid cells, and plays important roles in negatively regulating immune responses. CD200 is the only known ligand of CD200R and broadly distributed in a variety of cell types. Here we identified novel CD200 homologues, designated...

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Detalles Bibliográficos
Autores principales: Kojima, Toshiyuki, Tsuchiya, Kiichiro, Ikemizu, Shinji, Yoshikawa, Soichiro, Yamanishi, Yoshinori, Watanabe, Mamoru, Karasuyama, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098219/
https://www.ncbi.nlm.nih.gov/pubmed/27819346
http://dx.doi.org/10.1038/srep36457