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Multi-label ℓ(2)-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks

Protein-protein interaction (PPI) networks are naturally viewed as infrastructure to infer signalling pathways. The descriptors of signal events between two interacting proteins such as upstream/downstream signal flow, activation/inhibition relationship and protein modification are indispensable for...

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Detalles Bibliográficos
Autores principales: Mei, Suyu, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098220/
https://www.ncbi.nlm.nih.gov/pubmed/27819359
http://dx.doi.org/10.1038/srep36453