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Multi-label ℓ(2)-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks
Protein-protein interaction (PPI) networks are naturally viewed as infrastructure to infer signalling pathways. The descriptors of signal events between two interacting proteins such as upstream/downstream signal flow, activation/inhibition relationship and protein modification are indispensable for...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098220/ https://www.ncbi.nlm.nih.gov/pubmed/27819359 http://dx.doi.org/10.1038/srep36453 |