Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity

Intracerebral injection of the excitotoxic, endogenous tryptophan metabolite, quinolinic acid (QA), constitutes a chemical model of neurodegenerative brain disease. Complementary techniques were combined to examine the consequences of QA injection into medial prefrontal cortex (mPFC) of C57BL6 mice....

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Detalles Bibliográficos
Autores principales: Latif-Hernandez, Amira, Shah, Disha, Ahmed, Tariq, Lo, Adrian C., Callaerts-Vegh, Zsuzsanna, Van der Linden, Annemie, Balschun, Detlef, D’Hooge, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098239/
https://www.ncbi.nlm.nih.gov/pubmed/27819338
http://dx.doi.org/10.1038/srep36489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098239/
https://www.ncbi.nlm.nih.gov/pubmed/27819338
http://dx.doi.org/10.1038/srep36489

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